A Prospective And Randomized Double Blind Study To Compare The Effectiveness Of Prophylactic Granisetron Versus Pethidine For The Prevention Of Postoperative Shivering In Patients Undergoing Elective Thyroid Surgeries

MATERIALS AND METHODS 90 Patients randomly allocated into three groups- qroup P, qroup G, qroup S in each group 30patientswere Selected Group P Patients were given Inj Pethidine 25 mg intravenously 5 minutes before induction of general anaesthesia. Group G Patients were given Inj Granisetron 40 microgram /Kgintravenously 5 minutes before induction of general anaesthesia. Group S Patients were given Saline intravenously 5 minutes before induction of general anaesthesia. RESULTS Postoperative shivering graded after extubation at 15 and 30 minutes interval no shivering in Pethidine group 83.3% {n= 25} Granisetron, qroup 73% {n=22} Placebo qroup 27% {n=8} P value not significant between P & G group but significant in Placebo qroup {P <0.05}. shivering occurs at grade 3in pethidine group 7% [n=2] Granisetron group 10%[n=3], Placebo group 60%[n=18] P value statistically not significant between P & G groups but significant in Placebo qroup {P <0.05}. CONCLUSION From this study prophylactic use of both Pethidine and Granisetron were equally effective for the prevention of postoperative shivering

An Evaluation of the Effects of Marginal Design, Die Spacer, and Seating Force on the Marginal Fit of Cast Metal Crowns after Luting – An Invitro.

The marginal adaptation of cast metal crowns is essential for the success of cast restoration. The marginal design, die spacer and the seating force are considered as important factors effecting the marginal fit of cast metal crowns. Aims and Objectives; The aim and objectives of the present study is to evaluate the marginal fit of cast metal crowns 1.With three different marginal designs that are shoulder, shoulder with bevel and chamfer 2.With and without die spacer 3.Under seating forces 100N and 300N. METHODOLOGY: The study was done using 3 brass dies of 6mm height 10o taper with three different marginal designs shoulder, shoulder with 45o bevel and chamfer . 20 impressions of each metal die were made and casts were poured. 10 specimens of each group were coated with die spacer while the other 10 specimens were to serve as control group. Cementation done with GIC under two different seating forces (100N and 300N). The marginal discrepancy is determined by measuring the crown height before and after cementation. From this study it was concluded that specimen with combination of chamfer marginal design with die spacer under 300N seating force exhibited superior marginal adaptation.